Douglas CDMO is a specialist in the development and production of Softgel capsules and medicine fill.
Soft gelatin capsules are a delivery platform, containing an inner fill with an API. They lend themselves to various applications, including over-the-counter medications, dietary supplements, vitamins, nutraceuticals, and prescription pharmaceuticals. They are particularly suitable for liquid or semi-solid formulations, and commonly used for oil-based or lipid-soluble drugs.
The benefits of Softgel include:
- Addressing solubility issues.
- Protection of ingredients from exposure to light, air and moisture.
- Easier to swallow than hardshell capsules and tablets.
- A consistent and precise dose of the active ingredient.
- Enhanced shelf life.
Improved bioavailability
Softgel capsules stand out for their remarkable capability to enhance the bioavailability of certain compounds, guaranteeing optimal delivery of the active ingredient to its target site within the body. This enhanced bioavailability not only boosts therapeutic effectiveness but also maintains steady drug levels and may even reduce necessary dosages, ultimately leading to superior patient outcomes.
Abuse deterrent
Abuse-deterrent formulations target the known or expected routes of abuse, such as crushing to snort or dissolving to inject the drug substance. The field of abuse deterrence is emerging, with formulation technologies and evaluation methods evolving. Douglas CDMO has experience in developing these formulations and has laboratory partnerships with specialist capability to evaluate abuse deterrent features of proprietary dosage forms.
Commercial manufacturing
Douglas CDMO has two manufacturing sites, including state-of-the-art Softgel manufacturing equipment.
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